THE Western Port Highway was blocked between Eramosa and Bungower roads on Friday following a high-speed, two-car collision.
Police said one car appeared to have crossed double lines and crashed head on into another car 200 metres south of Eramosa Road, 12.45pm.
Three people – the driver and passenger in one car and the driver of the other – had to be cut free from the wreckage.
First Lieutenant Adam Carrigg, of Somerville CFA, said CFA crews from Langwarrin, Somerville, and Pearcedale, and Frankston SES, helped with the rescue.
Sergeant Bob Jung, of Somerville Highway Patrol, said two air ambulance helicopters ferried the drivers to the Alfred and Royal Melbourne hospitals, while the passenger was taken by road ambulance to the Royal Melbourne.
The speed limit on the Western Port Highway is 100kph. The weather at the time was fine and the roads were dry.